GC-MS analysis of methanolic extract of stem and root bark of Kirganelia reticulata for bioactive components

Abstract

Objective: To identify the bioactive components present in the stem and root bark extracts of Kirganelia reticulata.
Methods: The soxhlet extracted crude methanolic extracts of stem and root bark of Kirganelia reticulata were
analysed by GC-MS. Results: GC-MS analysis revealed the presence of 27 and 24 potential bioactive components in
stem and root bark extract of Kirganelia reticulata respectively. These components were mostly esters, phenols,
flavonoids, aldehydes, alkaloids, sterols and terpenoids with biological activity. Conclusion: Many of the bioactive
components identified in the study are multifunctional in nature with potent antioxidant, antimicrobial, antifungal,
antiviral, candidicide, hypocholesterolemic, anti-inflammatory, anti-cancer, anti-androgenic, antiasthma, diuretic and
hepatoprotective in nature justifying the use of this plant in traditional medicine for treating various ailments and also
providing an opportunity for identification of potential drug candidates