https://journals.mlacwresearch.org/index.php/ijfas IJFAS (ISSN: 2278-1404) is a peer-reviewed open-access journal publishing original research in fundamental and applied biological sciences. mLAC en-US International Journal of Fundamental and Applied Sciences (IJFAS) 2278-1404 <blockquote data-start="293" data-end="849"> <p data-start="295" data-end="849"><strong data-start="295" data-end="316">License Statement</strong><br data-start="316" data-end="319" />This work is licensed under a <a class="" href="https://creativecommons.org/licenses/by/4.0/" target="_new" rel="noopener" data-start="349" data-end="463">Creative Commons Attribution 4.0 International License (CC BY 4.0)</a>.<br data-start="464" data-end="467" />Authors who publish with <strong>International Journal of Fundamental and Applied Sciences (IJFAS)</strong> retain copyright of their articles and grant the journal the right of first publication.<br data-start="638" data-end="641" />This license allows others to share, use, and build upon the work—commercially or non-commercially—<strong data-start="740" data-end="782">as long as appropriate credit is given</strong> to the original authors and source, and any changes are indicated.</p> </blockquote> <blockquote data-start="851" data-end="983"> <p data-start="853" data-end="983">The journal encourages open access and supports the free exchange of knowledge while ensuring proper attribution of original work.</p> </blockquote> https://journals.mlacwresearch.org/index.php/ijfas/article/view/314 <p><em>Klebsiella </em>is a member of the fifth of the eight tribes of the Enterobacteriales family. The second most prevalent organism in the Enterobacteriaceae family is <em>Klebsiella</em> Species. &nbsp;It is a rod-shaped, facultative anaerobic bacillus that ferments lactose and is gram negative. Both hospital-acquired infections &amp; community-acquired infections are known to be frequently caused by them. Additionally, <em>Klebsiella</em> is the second most frequent cause of septicemia and bacteremia at hospital paediatric wards, particularly on intensive care units and premature infants. <em>Klebsiella</em> species are the causative agents of urinary tract infections, pneumonia, abrasion, muscle &amp; bacteremia and account for 3-8% of all nosocomial infections. To identify <em>Klebsiella</em> Species prevalence in different clinical samples along with to evaluate its antibiotic sensitivity method isolated from variety of clinical samples. Over the course of the six- month trial period, 74 samples in total were analyzed. To identify and isolate <em>Klebsiella</em> Species, each of them underwent direct microscopy and culture. In this study 42(57%) <em>Klebsiella</em> Species were isolated in female patients and 32(43%) were from male patients which is identified out of 74 clinical samples. Among the isolates, <em>K. pneumoniae </em>was identified in 65 cases (87.84%) and <em>K. oхytoca</em> in 9 cases (12.16%). Urine and Blood samples where the majority of <em>Klebsiella</em> Species were isolated from specimens. Higher sensitivity was seen with Colistin (100%), Tigecycline (94.59%) and Doxycycline (83.78%) among the 30 urine isolates tested, (83.33%) were sensitive to Fosfomycin by Kirbey-Bauer disc diffusion method. High resistance rates were recorded against: Ceftriaxone (87.84%) and Amoxicillin (79.73%). As an organism with a high prevalence that is growing more common due to antimicrobial agent resistance, <em>Klebsiella </em>Species may pose a risk to health.</p> <p>&nbsp;</p> Areeba Rehman Shadma Yaqoob Nighat Parveen Saumya Shukla Sanjay Kumar Vishwakarma Copyright (c) 2026 Areeba Rehman, Shadma Yaqoob, Nighat Parveen, Saumya Shukla, Sanjay Kumar Vishwakarma https://creativecommons.org/licenses/by/4.0 2025-12-30 2025-12-30 14 4 1 8 10.59415/ijfas.314