Dear Colleagues,

Throughout history, humans have harnessed the therapeutic potential of medicinal herbs and other natural substances for the treatment and prevention of diverse diseases. In the 20th century, numerous pharmaceuticals, sanctioned by regulatory authorities worldwide, were derived from these natural reservoirs. As a result, medicinal herbs and natural products have emerged as valuable reservoirs and catalysts for drug development.

Contemporary understanding recognizes that the etiology of many diseases is characterized by multifaceted processes. Therefore, the effective management of these ailments necessitates interventions that target multiple pathways. Conventional drugs, consisting of single molecular entities, typically focus on singular pathways or specific physiological functions. In contrast, traditional folk medicine employs one or more natural products to create extracts, infusions, and decoctions. Even a single medicinal herb preparation may contain an array of bioactive molecules, numbering potentially in the hundreds or thousands. These molecules exert their effects on various organs and systems, either enhancing or inhibiting the actions of other bioactive constituents within the preparation. For instance, it is not uncommon for antibacterial and antiviral medications to exhibit immunomodulatory properties. Similarly, anti-cancer therapies may activate or suppress diverse pathways implicated in cancer initiation and progression.

In the context of this Special Issue, our objective is to consolidate and assess the most recent research advancements, elucidating the natural products capable of concurrently targeting multiple pathways and physiological functions. Such insights hold promise for the efficacious treatment of multifactorial diseases.


Dr. Sushil Kumar Middha, Associate Prof, mLAC      Scholar

Dr. Ligi Milesh , UW- Madison,  Scholar

Dr. Usha T.  Associate Prof, mLAC Scholar

Manuscript Submission Information

Manuscripts should be submitted online at the International Journal of Fundamental and Applied Sciences by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. IJFAS is an international peer-reviewed open-access monthly journal published by mLAC.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open-access journal is paid by mLAC-Research so for publishing authors it is ZERO. Submitted papers should be well formatted and use good English. 


  • natural products
  • medicinal herbs
  • marine products
  • Computer-Aided Drug Design
  • In vivo/in vitro studies
  • Pharmacokinetics/Dynamics studies
  • animal products
  • bioactive compounds
  • multifactorial diseases
  • multi-targeting phytochemicals